About half of a healthy epidermis should be made up of ceramides. But when ceramides are in short supply due to environmental factors, behaviors, or external irritants such as chemicals or harsh cleansers, the cells of the epidermis are no longer held firmly in place and the “wall” is no longer strong and impenetrable. This weakened barrier makes the skin more susceptible to outside irritants, accelerating the decline of skin health. As ceramide levels decline the cells begin to break free from the rigid structure of the epidermis, leading to that feeling of tight and dry, sensitive skin. With a weakened barrier, your skin can’t hold the cells ofthe stratum corneum together allowing moisture to escape the skin easily, leaving skin rough and dehydrated. A weakened barrier also makes your skin more vulnerable to infection, inflammation and flare ups of skin conditions like eczema and atopic dermatitis.